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Life After
Bone Marrow Transplant Is
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Hematology and Bone Marrow Transplant

Department of Hematology and Bone Marrow Transplant

The field of haematology covers a broad spectrum of blood disorders. We provide a comprehensive, one-stop service for the diagnostic investigations and treatment of a wide range of benign as well as malignant blood and bone marrow disorders.

A bone marrow transplant is a procedure that infuses healthy blood-forming stem cells into your body to replace your damaged or diseased bone marrow. A bone marrow transplant is also called a stem cell transplant.

Patient might need a bone marrow transplant if patient’s bone marrow stops working and does not produce enough healthy blood cells.

Why choose us for Hematology and BMT services?

At Global Hospitals, you are more than just your disease. Our Haematologists understand the daily challenges a blood condition can present. They look beyond your blood disease to provide care for your disease through a diverse range of services for you.

Patients have access to a full range of treatment options, including standard and cutting-edge, innovative treatments. Our team approach with one-stop care plus efficient scheduling means accurate, rapid assessment, timely start of treatment and excellent follow-up care.

At Global Hospitals Mumbai, Clinical Haematologists are specialised in benign hematology, haemato-oncology and bone marrow transplantation.

Our Diagnosis Capabilities

Global Hospitals, Mumbai is one of the best hospitals in India with the expertise & experience for the diagnosis of haematological conditions. Diagnosis of haematological conditions requires a thorough physical examination and assessment of the patient’s medical history, followed by blood work and a possible bone marrow test.

Treatment of diseases by Hematology and Bone Marrow Transplant

Haematologists at Global Hospitals, Mumbai constantly work to make patient care better and more convenient. Bone marrow transplants can benefit people with a variety of both cancerous (malignant) and noncancerous (benign) diseases.

We at Global Hospitals have total of 5 bedded international standard bone marrow transplant unit. At Global Hospitals, we are capable of doing both autologous (collections of stem cells from patient) and allogenic (collections of stem cells from related donor). Doctors at Global Hospitals have expertise in doing alternate/ unrelated donor transplants as well haploidentical donor(half matched) transplant.

The dept of haematology provides state of the art care for wide spectrum of diseases including:

  • Acute leukaemia
  • Adrenoleukodystrophy
  • Aplastic anaemia
  • Bone marrow failure syndromes
  • Chronic leukaemia
  • Hemoglobinopathies
  • Hodgkin’s lymphoma
  • Immuno deficiencies
  • Inborn errors of metabolism
  • Multiple myeloma
  • Myelodysplastic syndromes
  • Non-Hodgkin’s lymphoma
  • Plasma cell disorders
  • Primary amyloidosis
Autologous bone marrow transplant

This type of transplant involves the use of a patient’s stem cells. They involve harvesting the patient’s cell before damaging therapy like chemotherapy or radiation. The cells return to the body after the treatment is done. It can only be used for patients with healthy bone marrow. The technician doing the collection freezes the collected stem cells before storing them for later use. Using this transplant offers various advantages over stem cells from another donor. For example, the cells are always compatible. Global Hospitals has some of the best surgeons for autologous bone marrow transplant in Mumbai. 

It is used for people who undergo high doses of chemotherapy and radiation for curing their diseases. These treatments are likely to damage the marrow. Autologous BMT helps to restore the damage. In this type of transplant, doctors generally collect or harvest stem cells called peripheral blood stem cells. This process is more straightforward than an allogeneic transplant, which acquires stem cells from another donor. It does not require operations or general anaesthesia. When undergoing an autologous or allogeneic BMT, patients are given medicines to increase the number of stem cells in their blood.

Further, the stem cells are filtered from the blood before the patient goes through high doses of cancer treatment like chemo, etc. Finally, healthy bone marrow cells are infused back into the body of the patient. The hospital has some of the best doctors for autologous bone marrow transplant in Mumbai. 

There are no side effects to the transplant as such. But occasionally, patients tend to experience a funny taste in mouth, chills, nausea, etc. The urine could also be tinged red for the first 24 hours post-transplantation. 

Allogeneic BMT

An allogeneic stem cell transplant utilizes healthy blood stem cells from a donor to replace the diseased or damaged bone marrow. An allogeneic stem cell transplant is also known as an allogeneic bone marrow transplant. The donor in this type of operation can be a family member, an acquaintance, or an unknown person. The blood stem cells utilized in an allogeneic stem cell transplant could be: 

  • Gathered from the donor’s blood
  • Gathered from the bone marrow within the donor’s hipbone 
  • Gathered from the blood of a donated umbilical cord

Before receiving the transplant, the patient will receive high doses of chemotherapy or radiation for destroying the diseased cells and prepare the body for the donor cells. 

Allogeneic BMT can be a choice for people with a wide range of cancerous and noncancerous diseases, like acute leukaemia, adrenoleukodystrophy, aplastic anaemia, chronic leukaemia, etc. Global Hospitals has some of the best surgeons for allogeneic bone marrow transplants in Mumbai. The different types of allogeneic transplants based on the source of stem cells include: 

  • Allogeneic BMT using related donor: Here, the stem cells are extracted from a relative. 
  • Allogeneic BMT using matched unrelated donor: Here, the donor is searched by doctors from an international registry.
  • Allogeneic BMT using haploidentical donors: The procedure utilizes HLA half-matched (haplotype) donors like biological parents, children, or half-matched siblings.
  • Allogeneic transplant using the blood of umbilical cord: Here, the blood cells are extracted from the umbilical cord of a new-born baby. 
  • Reduced-Intensity conditioning allogeneic transplants: This is an option for patients who can’t endure a full-intensity or myeloablative allogeneic transplant.

The following procedures collect the stem cells 

  • Peripheral blood stem cells: They are gathered by a process called apheresis. This takes place in the therapeutic apheresis outpatient unit. During the procedure, blood from a large vein goes through a central venous catheter, to a cell separation machine. The peripheral blood stem cells are collected, and the remaining blood is returned.
  • Bone Marrow Harvest: In this procedure, a small portion of bone marrow is collected by a needle that goes through the skin, inside the marrow cavity of the hip bone. 

The side effects of this type of transplant include increased risk of infections, excessive bleeding, graft-versus-host disease, etc. The hospital has some of the best doctors for allogeneic bone marrow transplants in Mumbai.

Our Doctors – Hematologists

The Department of Haematology and Bone Marrow Transplant at Global Hospitals is one of the finest hospital for haematological services and bone marrow transplantation in Mumbai for delivering the best treatment for cancer and blood diseases. The patients have unlimited access to a team of best doctors for the treatment of cancer and blood disorders. The hospital has some of the best clinical haematology specialists in Mumbai. They are highly experienced and well-trained physicians. We make sure that the patients receive complete care from all other allied specialists, who coordinate the best effort in their journey to cure blood cancers.

Dr Abhay Bhave

MBBS, MD

Senior Consultant

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Dr Shrinath Kshirsagar

MBBS, MD, DNB, PDF

Consultant

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Dr Akshay Shah

MBBS, DNB, DNB

Consultant

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We are with you in your journey to better health

A consultation with our panel of doctors, specialists and surgeons will help you determine what kind of services you may need to help diagnose and treat your condition. If you or someone in your family or friend’s circle are facing any health issues, please get in touch with us, we are here for you.

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